Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8711532 | 0.96 | NPC1 (0.38) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL8710077 | 0.87 | MEN1 (0.40) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL8048299 | 0.86 | PKM (0.39) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL8042895 | 0.86 | ALDH1A1 (0.40) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL8045215 | 0.84 | PDK1 (0.47) | ALDH1A1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8032479 | 0.83 | ALDH1A1 (0.47) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL8043014 | 0.83 | RECQL (0.49) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL8042782 | 0.81 | PKM (0.39) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL8052304 | 0.81 | ALDH1A1 (0.49) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL8044412 | 0.81 | SMN1; SMN2 (0.44) | ALDH1A1NPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |