SCHEMBL8042854

SCHEMBL8042854

O=CNc1nnc(S)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2440995 0.74
SCHEMBL2437459 0.73
SCHEMBL9893162 0.68 CA1 (0.53)
SCHEMBL2442388 0.68 SMN1; SMN2 (0.41)
SCHEMBL18542005 0.68 SMN1; SMN2 (0.51)
SCHEMBL2445764 0.68 GLS (0.37)
SCHEMBL2446415 0.68 CA1 (0.53)
SCHEMBL16404631 0.67 ALDH1A1 (0.50)
SCHEMBL14501008 0.67 CA2 (0.58)
SCHEMBL2441632 0.66 SMN1; SMN2 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1431813-B1 Photothermographic material with high iodide content and image forming method using same FUJI PHOTO FILM CO LTD (JP) 2007-02-14 EP disclosed
US-7175978-B2 Silver salt photothermographic dry imaging material KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-02-13 US disclosed
US-20070003886-A1 SILVER SALT PHOTOTHERMOGRAPHIC DRY IMAGING MATERIAL KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-01-04 US disclosed
US-6143765-A ENZYME IHIBITORS OF PROTEIN SUGEN, INC. (US) 2000-11-07 US disclosed
US-6080772-A 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY SUGEN, INC. (US) 2000-06-27 US disclosed
US-5883110-A ORGANIC MOLECULES CAPABLE OF INHIBITING PROTEIN TYROSINE PHOSPHATASE ACTIVITY, AND THE USE OF SUCH MOLECULES TO TREAT VARIOUS DISEASE STATES INCLUDING DIABETES MELLITUS, GLIOMA, MELANOMA, KAPOSI'S SARCOMA, HEMANGIOMA, OVARIAN CANCER, BREAST SUGEN, INC. (US) 1999-03-16 US disclosed