Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8046042 | 0.88 | SMN1; SMN2 (0.46) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL8047523 | 0.83 | PARP1 (0.53) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL8042395 | 0.82 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL8042404 | 0.82 | MAPT (0.45) | MEN1KMT2AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL8043606 | 0.80 | MEN1 (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL8046634 | 0.80 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL8043408 | 0.79 | KMT2A (0.38) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL8050068 | 0.79 | MEN1 (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL8044906 | 0.79 | MEN1 (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL8032889 | 0.79 | ALDH1A1 (0.37) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |