Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8045211 | 0.90 | KMT2A (0.48) | MAPTTSHRLMNAMEN1KMT2A | |
| SCHEMBL8047523 | 0.90 | PARP1 (0.53) | MAPTTSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8042877 | 0.85 | HDAC6 (0.44) | MAPTTSHRLMNAMEN1KMT2A | |
| SCHEMBL8032967 | 0.83 | RAB9A (0.48) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8048236 | 0.82 | MAPT (0.44) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8043002 | 0.82 | MEN1 (0.43) | MAPTTSHRLMNAMEN1KMT2A | |
| SCHEMBL8043408 | 0.82 | KMT2A (0.38) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8048496 | 0.81 | MEN1 (0.43) | MAPTTSHRLMNAMEN1KMT2A | |
| SCHEMBL8042990 | 0.80 | RAB9A (0.47) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8044267 | 0.79 | PARP1 (0.49) | MAPTTSHRLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |