Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 4/20 | 0.35 |
| ▸ | JAK1 | P23458 | 4/20 | 0.35 |
| ▸ | JAK3 | P52333 | 4/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7950685 | 0.94 | ALDH1A1 (0.43) | ALDH1A1CASP1PIK3CBKDM4EL3MBTL1 | |
| SCHEMBL13099804 | 0.91 | ADORA3 (0.40) | ALDH1A1CASP1PIK3CBKDM4EL3MBTL1 | |
| SCHEMBL8054923 | 0.87 | RAB9A (0.42) | ALDH1A1CASP1PIK3CBKDM4EL3MBTL1 | |
| SCHEMBL7952511 | 0.87 | ALDH1A1 (0.50) | ALDH1A1CASP1PIK3CBKDM4EL3MBTL1 | |
| SCHEMBL8049613 | 0.86 | ATM (0.42) | ALDH1A1CASP1PIK3CBKDM4EL3MBTL1 | |
| SCHEMBL8037402 | 0.84 | APOBEC3A (0.46) | ALDH1A1CASP1PIK3CBKDM4EL3MBTL1 | |
| SCHEMBL8043064 | 0.84 | EGFR (0.41) | ALDH1A1CASP1PIK3CBKDM4EL3MBTL1 | |
| SCHEMBL7948913 | 0.84 | LMNA (0.41) | ALDH1A1CASP1PIK3CBKDM4EL3MBTL1 | |
| SCHEMBL8049800 | 0.83 | KDM4E (0.42) | ALDH1A1CASP1PIK3CBKDM4EL3MBTL1 | |
| SCHEMBL7942597 | 0.83 | CCNT1 (0.40) | CASP1JAK2JAK1JAK3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009038385-A2 | NOVEL COMPOUNDS HAVING INDAZOLE FRAMEWORKS, METHODS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHOONGWAE PHARMA CORPORATION (KR) | 2009-03-26 | — | — | WO | disclosed |