Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 2/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30888586 | 0.75 | HTT (0.38) | ALDH1A1MAPTMEN1KMT2ATNF | |
| SCHEMBL5573410 | 0.74 | PTPN1 (0.43) | ALDH1A1MAPTMEN1KMT2ADPP4 | |
| SCHEMBL1258695 | 0.71 | PTPN1 (0.42) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL8043075 | 0.69 | DHODH (0.43) | KDM4EHPGD | |
| SCHEMBL8041784 | 0.68 | DPP4 (0.36) | ALDH1A1MAPTKDM4EKMT2AMAPK1 | |
| SCHEMBL8031083 | 0.68 | DPP4 (0.36) | ALDH1A1MAPTKDM4EKMT2AMAPK1 | |
| SCHEMBL17774715 | 0.65 | TDP1 (0.41) | ALDH1A1MAPTHPGDHSD17B10USP2 | |
| SCHEMBL728615 | 0.64 | DPP4 (0.37) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL30888552 | 0.64 | HSD17B10 (0.40) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL7940169 | 0.63 | PTPN1 (0.41) | ALDH1A1MAPTHPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686144-B1 | NEW COMPOUNDS | UNIV MARYLAND (US) | 2000-04-19 | — | — | EP | disclosed |
| US-5688945-A | Compounds | ASTRA AKTIEBOLAG (SE) | 1997-11-18 | — | — | US | disclosed |
| US-5661183-A | 3-hydroxy anthanilic acid derivatives | THE UNIVERSITY OF MARYLAND (US) | 1997-08-26 | — | — | US | disclosed |
| EP-0686144-A1 | NEW COMPOUNDS | Astra Aktiebolag (SE) | 1995-12-13 | — | — | EP | disclosed |
| WO-1994019315-A1 | NEW COMPOUNDS | ASTRA AKTIEBOLAG (SE) | 1994-09-01 | — | — | WO | disclosed |