SCHEMBL8043547

SCHEMBL8043547

CCCCC1(c2ccccc2OCC)CCC(C(=O)O)CC1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.40
GLA P06280 1/20 0.40
TSHR P16473 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
RXRA P19793 1/20 0.37
HNF4A P41235 1/20 0.37
PDE4B Q07343 1/20 0.37
LMNA P02545 2/20 0.36
KCNA3 P22001 2/20 0.36
S1PR5 Q9H228 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
MAPK1 P28482 1/20 0.35
GAA P10253 1/20 0.35
POLB P06746 2/20 0.35
HCRTR1 O43613 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8044997 0.96 L3MBTL1 (0.39) L3MBTL1GLATSHRSMN1; SMN2RXRA
SCHEMBL8045475 0.93 GLA (0.41) L3MBTL1GLATSHRSMN1; SMN2PDE4B
SCHEMBL7511978 0.88 PDE4B (0.40) PDE4BLMNAS1PR5MEN1KMT2A
SCHEMBL7507058 0.88 PDE4B (0.41) L3MBTL1GLATSHRPDE4BLMNA
SCHEMBL7514436 0.86 HTT (0.43) PDE4BKCNA3MEN1KMT2A
SCHEMBL10790633 0.83 PDE4B (0.38) TSHRPDE4BLMNAS1PR5MEN1
SCHEMBL7513588 0.83 CASP1 (0.41) L3MBTL1S1PR5MEN1KMT2APOLB
SCHEMBL8562488 0.81 HSD11B1 (0.39) S1PR5MEN1KMT2APOLB
SCHEMBL8078671 0.81 TSHR (0.41) L3MBTL1GLATSHRSMN1; SMN2RXRA
SCHEMBL8729803 0.81 CASP1 (0.37) S1PR5MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0805134-B1 NOVEL LIQUID-CRYSTAL COMPOUNDS BEARING DIENYL MOIETY AND LIQUID-CRYSTAL COMPOSITION CHISSO CORP (JP) 2000-08-30 EP disclosed
US-6086964-A Liquid crystalline compound having dienyl moiety and liquid crystal composition CHISSO CORPORATION (JP) 2000-07-11 US disclosed
EP-0733692-B1 Liquid crystalline compound, liquid crystal composition containing the same, and display device CHISSO CORP (JP) 2000-06-14 EP disclosed
US-6001275-A LIQUID CRYSTALLINE COMPOUND WHICH HAS A LARGE RATIO OF ELASTIC CONSTANTS, HAS A LOW VISCOSITY, EXCELLENT MISCIBILITY WITH OTHER LIQUID CRYSTALLINE COMPOUND, CHEMICALLY STABLE; HAVING AN UNCONJUGATED ALKADIENYL GROUP AT A SIDE CHAIN. CHISSO CORPORATION (JP) 1999-12-14 US disclosed
US-5833879-A LOW TEMPERATURE MISCIBILITY AND COMPATIBILITY WITH OTHER LIQUID CRYSTAL COMPOUNDS; DISPLAYS CONTAINING MIXTURES OF AT LEAST TWO COMPOUNDS, PHYSICAL PROPERTIES CHISSO CORPORATION (JP) 1998-11-10 US disclosed
US-5714088-A TRIFLUOROMETHYL- OR -METHOXYPHENYL-SUBSTITUTED BRANCHED ALKYL-SUBSTITUTED CYCLOHEXANES; LARGE POSITIVE VALUE OF DIELECTRIC ANISOTROPY; VERY LOW VISCOSITY; HIGH VOLTAGE HOLDING RATIO(SPECIFIC RESISTANCE); UV STABILITY CHISSO CORPORATION (JP) 1998-02-03 US disclosed
EP-0805134-A1 NOVEL LIQUID-CRYSTAL COMPOUNDS BEARING DIENYL MOIETY AND LIQUID-CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1997-11-05 EP disclosed