Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | GLP1R | P43220 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033779 | 0.77 | EGLN1 (0.49) | EGLN1RAB9APOLBHPGDMEN1 | |
| SCHEMBL8047141 | 0.77 | EGLN1 (0.38) | EGLN1RAB9ASMN1; SMN2POLBHPGD | |
| SCHEMBL8042483 | 0.73 | KDM4E (0.49) | RAB9ASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL8032372 | 0.72 | — | — | |
| SCHEMBL8043836 | 0.70 | ICAM1 (0.40) | RAB9ASMN1; SMN2NPC1LMNAALDH1A1 | |
| SCHEMBL8048057 | 0.70 | RAB9A (0.39) | EGLN1RAB9ASMN1; SMN2POLBHPGD | |
| SCHEMBL8042567 | 0.69 | RAB9A (0.46) | EGLN1RAB9ASMN1; SMN2HPGDKMT2A | |
| SCHEMBL8048521 | 0.68 | POLB (0.36) | EGLN1RAB9ASMN1; SMN2POLBHPGD | |
| SCHEMBL8045613 | 0.67 | RAB9A (0.44) | RAB9ASMN1; SMN2POLBHPGDMEN1 | |
| SCHEMBL8033105 | 0.64 | POLB (0.33) | EGLN1RAB9ASMN1; SMN2POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |