Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043655 | 0.95 | ITGB3 (0.41) | ITGB3ITGA2BALOX15ALDH1A1USP2 | |
| SCHEMBL8034394 | 0.93 | ITGB3 (0.42) | ITGB3ITGA2BALOX15ALDH1A1KDM4E | |
| SCHEMBL8044047 | 0.88 | ITGB3 (0.38) | ITGB3ITGA2BALOX15ALDH1A1RAB9A | |
| SCHEMBL8034809 | 0.83 | ABL1 (0.40) | ITGB3ITGA2BALOX15ALDH1A1OPRL1 | |
| SCHEMBL8044020 | 0.82 | ITGB3 (0.55) | ITGB3ITGA2BALOX15RAB9A | |
| Hydrochloric Acid SCHEMBL8034450 | 0.81 | ALOX15 (0.56) | ITGB3ITGA2BALOX15RAB9A | |
| SCHEMBL8043708 | 0.77 | ITGB3 (0.41) | ITGB3ITGA2BALOX15ALDH1A1KDM4E | |
| SCHEMBL8044034 | 0.77 | ITGB3 (0.42) | ITGB3ITGA2BALOX15ALDH1A1RAB9A | |
| SCHEMBL8045537 | 0.75 | ITGB3 (0.51) | ITGB3ITGA2BALOX15ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8043473 | 0.75 | ALOX15 (0.58) | ITGB3ITGA2BALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057324-A | HAVE GPIIB/IIIA RECEPTOR ANTAGONIZING ACTIVITY AND ARE USEFUL FOR AMELIORATING ISCHEMIC CARDIAC DISORDERS, FOR AMELIORATING CEREBROVASCULAR DISORDERS, AND FOR AMELIORATING PERIPHERAL ARTERY DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD (JP) | 2000-05-02 | — | — | US | claimed |
| EP-0905129-A1 | SUBSTITUTED AMIDINOBENZENE DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1999-03-31 | — | — | EP | claimed |
| US-6057324-A | HAVE GPIIB/IIIA RECEPTOR ANTAGONIZING ACTIVITY AND ARE USEFUL FOR AMELIORATING ISCHEMIC CARDIAC DISORDERS, FOR AMELIORATING CEREBROVASCULAR DISORDERS, AND FOR AMELIORATING PERIPHERAL ARTERY DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0905129-A1 | SUBSTITUTED AMIDINOBENZENE DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1999-03-31 | — | — | EP | disclosed |