Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 5/20 | 0.34 |
| ▸ | F2 | P00734 | 4/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | ABL2 | P42684 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034809 | 0.89 | ABL1 (0.40) | ITGB3ITGA2BALOX15ABL1EGFR | |
| SCHEMBL8044047 | 0.87 | ITGB3 (0.38) | ITGB3ITGA2BALOX15F10F2 | |
| SCHEMBL8034558 | 0.79 | ITGB3 (0.74) | ITGB3ITGA2BALOX15F10PRSS1 | |
| SCHEMBL8034394 | 0.78 | ITGB3 (0.42) | ITGB3ITGA2BALOX15ABL1EGFR | |
| SCHEMBL8043655 | 0.77 | ITGB3 (0.41) | ITGB3ITGA2BALOX15F10F2 | |
| SCHEMBL8043710 | 0.75 | ITGB3 (0.40) | ITGB3ITGA2BALOX15ALDH1A1 | |
| SCHEMBL8052283 | 0.71 | ITGB3 (0.42) | ITGB3ITGA2BALOX15 | |
| SCHEMBL8045526 | 0.71 | ITGB3 (0.56) | ITGB3ITGA2BALOX15F10PRSS1 | |
| SCHEMBL8323744 | 0.70 | ITGB3 (0.65) | ITGB3ITGA2BALOX15ALDH1A1 | |
| SCHEMBL8784809 | 0.70 | ITGB3 (0.73) | ITGB3ITGA2BALOX15F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057324-A | HAVE GPIIB/IIIA RECEPTOR ANTAGONIZING ACTIVITY AND ARE USEFUL FOR AMELIORATING ISCHEMIC CARDIAC DISORDERS, FOR AMELIORATING CEREBROVASCULAR DISORDERS, AND FOR AMELIORATING PERIPHERAL ARTERY DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0905129-A1 | SUBSTITUTED AMIDINOBENZENE DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1999-03-31 | — | — | EP | disclosed |