Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | ABL2 | P42684 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034809 | 0.91 | ABL1 (0.40) | ITGB3ITGA2BALOX15GAAGSK3B | |
| SCHEMBL8043655 | 0.90 | ITGB3 (0.41) | ITGB3ITGA2BALOX15F2SMN1; SMN2 | |
| SCHEMBL8043710 | 0.88 | ITGB3 (0.40) | ITGB3ITGA2BALOX15BACE1SMN1; SMN2 | |
| SCHEMBL8045537 | 0.87 | ITGB3 (0.51) | ITGB3ITGA2BALOX15F2ALDH1A1 | |
| SCHEMBL8044020 | 0.81 | ITGB3 (0.55) | ITGB3ITGA2BALOX15F2MEN1 | |
| SCHEMBL8034394 | 0.81 | ITGB3 (0.42) | ITGB3ITGA2BALOX15SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8034450 | 0.80 | ALOX15 (0.56) | ITGB3ITGA2BALOX15F2MEN1 | |
| SCHEMBL8044034 | 0.74 | ITGB3 (0.42) | ITGB3ITGA2BALOX15SMN1; SMN2GSK3B | |
| SCHEMBL8688555 | 0.73 | ITGB3 (0.54) | ITGB3ITGA2BALOX15F2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8045554 | 0.73 | BACE1 (0.36) | ITGB3ITGA2BALOX15F2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057324-A | HAVE GPIIB/IIIA RECEPTOR ANTAGONIZING ACTIVITY AND ARE USEFUL FOR AMELIORATING ISCHEMIC CARDIAC DISORDERS, FOR AMELIORATING CEREBROVASCULAR DISORDERS, AND FOR AMELIORATING PERIPHERAL ARTERY DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD (JP) | 2000-05-02 | — | — | US | claimed |
| EP-0905129-A1 | SUBSTITUTED AMIDINOBENZENE DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1999-03-31 | — | — | EP | claimed |
| US-6057324-A | HAVE GPIIB/IIIA RECEPTOR ANTAGONIZING ACTIVITY AND ARE USEFUL FOR AMELIORATING ISCHEMIC CARDIAC DISORDERS, FOR AMELIORATING CEREBROVASCULAR DISORDERS, AND FOR AMELIORATING PERIPHERAL ARTERY DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0905129-A1 | SUBSTITUTED AMIDINOBENZENE DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1999-03-31 | — | — | EP | disclosed |