Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049900 | 0.76 | SMN1; SMN2 (0.41) | KMT2ATDP1PKMSMN1; SMN2CA12 | |
| SCHEMBL8044768 | 0.74 | KMT2A (0.45) | KMT2ATDP1PKMSMN1; SMN2CA12 | |
| SCHEMBL5739940 | 0.64 | KMT2A (0.44) | KMT2ATDP1PKMSMN1; SMN2CA12 | |
| SCHEMBL8044837 | 0.64 | — | — | |
| SCHEMBL20751417 | 0.64 | PKM (0.47) | KMT2ATDP1PKMSMN1; SMN2L3MBTL1 | |
| SCHEMBL14309038 | 0.63 | PKM (0.45) | KMT2ATDP1PKMSMN1; SMN2CA12 | |
| SCHEMBL4394864 | 0.63 | NOS2 (0.54) | KMT2ATDP1PKMSMN1; SMN2CA12 | |
| SCHEMBL4161939 | 0.62 | SMN1; SMN2 (0.49) | KMT2ATDP1PKMSMN1; SMN2L3MBTL1 | |
| SCHEMBL68851 | 0.62 | CYP4Z1 (0.62) | KMT2APKMSMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL24541184 | 0.62 | KDM4E (0.53) | KMT2APKMSMN1; SMN2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |