Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 9/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8710115 | 0.88 | FBP1 (0.30) | FBP1PDK1 | |
| SCHEMBL8043989 | 0.80 | FBP1 (0.42) | FBP1PDK1HTR7FDPSFLT3 | |
| SCHEMBL8050950 | 0.79 | FBP1 (0.39) | FBP1PDK1HTR7FDPSFLT3 | |
| SCHEMBL8050943 | 0.79 | FBP1 (0.42) | FBP1PDK1HTR7FDPSFLT3 | |
| SCHEMBL8042936 | 0.76 | RAB9A (0.32) | — | |
| SCHEMBL8033274 | 0.74 | FBP1 (0.41) | FBP1PDK1HTR7FLT3KDM1A | |
| SCHEMBL8044818 | 0.71 | RAB9A (0.41) | FBP1PDK1HTR7KDM1A | |
| SCHEMBL8048086 | 0.70 | FBP1 (0.39) | FBP1PDK1HTR7FDPS | |
| SCHEMBL8044148 | 0.70 | — | — | |
| SCHEMBL8050844 | 0.69 | ALDH1A1 (0.47) | FBP1PDK1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |