Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 12/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033274 | 0.80 | FBP1 (0.41) | FBP1PDK1HTR7FLT3KDM1A | |
| SCHEMBL8043899 | 0.80 | FBP1 (0.39) | FBP1PDK1HTR7FLT3KDM1A | |
| SCHEMBL8050950 | 0.80 | FBP1 (0.39) | FBP1PDK1HTR7FLT3KDM1A | |
| SCHEMBL8050943 | 0.80 | FBP1 (0.42) | FBP1PDK1HTR7FLT3KDM1A | |
| SCHEMBL8044818 | 0.78 | RAB9A (0.41) | FBP1PDK1HTR7KDM1ANPC1 | |
| SCHEMBL8042933 | 0.72 | DCUN1D1 (0.37) | FBP1PDK1NPC1RAB9AKMT2A | |
| SCHEMBL8051281 | 0.72 | MEN1 (0.39) | FBP1PDK1HTR7FDPSRECQL | |
| SCHEMBL8042935 | 0.71 | NPC1 (0.40) | FBP1PDK1HTR7NPC1PKM | |
| SCHEMBL8045945 | 0.71 | RAB9A (0.46) | FBP1NPC1RAB9A | |
| SCHEMBL7114230 | 0.71 | FBP1 (0.70) | FBP1PDK1HTR7FLT3KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |