Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8035014 | 0.89 | TARBP2 (0.42) | TARBP2LMNAMMP13PDCD4NPC1 | |
| SCHEMBL3841049 | 0.85 | FFAR1 (0.49) | LMNAMMP13NPC1RAB9AMAPT | |
| SCHEMBL8052162 | 0.85 | LMNA (0.43) | TARBP2LMNAMMP13PDCD4NPC1 | |
| SCHEMBL3839635 | 0.76 | FFAR1 (0.45) | LMNAMMP13NPC1RAB9AMAPT | |
| SCHEMBL31629479 | 0.73 | DAO (0.44) | TARBP2LMNAMMP13PDCD4NPC1 | |
| SCHEMBL11876582 | 0.73 | BRD4 (0.46) | TARBP2LMNAPDCD4MAPTALDH1A1 | |
| SCHEMBL18785380 | 0.73 | LMNA (0.49) | TARBP2LMNAMMP13PDCD4NPC1 | |
| SCHEMBL8435193 | 0.73 | SMN1; SMN2 (0.42) | TARBP2LMNAMMP13PDCD4NPC1 | |
| SCHEMBL18785383 | 0.72 | GABRA2 (0.49) | LMNAMMP13NPC1RAB9AMAPT | |
| SCHEMBL10595807 | 0.72 | DAO (0.49) | NPC1GAAPOLBALDH1A1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143774-A | DRUGS AS HYPOTENSIVE AGENTS | HOECHST MARION ROUSSEL (FR) | 2000-11-07 | — | — | US | disclosed |