Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3840799 | 0.86 | FFAR1 (0.46) | LMNAMMP13SMN1; SMN2MAPTPOLB | |
| SCHEMBL8043911 | 0.85 | TARBP2 (0.46) | LMNATARBP2MMP13PDCD4L3MBTL1 | |
| SCHEMBL8035014 | 0.82 | TARBP2 (0.42) | LMNATARBP2MMP13PDCD4L3MBTL1 | |
| SCHEMBL3841049 | 0.71 | FFAR1 (0.49) | LMNAMMP13SMN1; SMN2MAPTPOLB | |
| SCHEMBL11876582 | 0.70 | BRD4 (0.46) | LMNATARBP2PDCD4L3MBTL1SMN1; SMN2 | |
| SCHEMBL18785380 | 0.70 | LMNA (0.49) | LMNATARBP2MMP13PDCD4L3MBTL1 | |
| SCHEMBL31629479 | 0.70 | DAO (0.44) | LMNATARBP2MMP13PDCD4L3MBTL1 | |
| SCHEMBL18785383 | 0.70 | GABRA2 (0.49) | LMNAMMP13SMN1; SMN2MAPTPOLB | |
| SCHEMBL3839635 | 0.69 | FFAR1 (0.45) | LMNAMMP13SMN1; SMN2MAPTPOLB | |
| SCHEMBL8435193 | 0.68 | SMN1; SMN2 (0.42) | LMNATARBP2MMP13PDCD4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143774-A | DRUGS AS HYPOTENSIVE AGENTS | HOECHST MARION ROUSSEL (FR) | 2000-11-07 | — | — | US | disclosed |