Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 19/20 | 0.57 |
| ▸ | LMNA | P02545 | 11/20 | 0.57 |
| ▸ | HTT | P42858 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032815 | 0.89 | SMN1; SMN2 (0.52) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL8044963 | 0.86 | ALDH1A1 (0.42) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL8043953 | 0.86 | TDP1 (0.47) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL8042731 | 0.85 | ALDH1A1 (0.41) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL8032329 | 0.85 | RECQL (0.53) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL8042535 | 0.84 | PTGS2 (0.44) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL8046282 | 0.84 | SMN1; SMN2 (0.49) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL8032354 | 0.82 | ALDH1A1 (0.46) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL8044812 | 0.82 | ALDH1A1 (0.52) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL8045341 | 0.82 | ALDH1A1 (0.49) | ALDH1A1LMNAHTTSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |