Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.36 |
| ▸ | TUBB | P07437 | 3/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (-)-Steganacin SCHEMBL10065023 | 0.89 | LMNA (0.57) | CYP3A4LMNAPOLBHTTMAPT | |
| Steganacin SCHEMBL66054 | 0.89 | LMNA (0.57) | CYP3A4LMNAPOLBHTTMAPT | |
| Steganacin SCHEMBL14138211 | 0.89 | LMNA (0.57) | CYP3A4LMNAPOLBHTTMAPT | |
| SCHEMBL19050768 | 0.81 | CYP3A4 (0.53) | CYP3A4LMNAPOLBHTTCYP2D6 | |
| SCHEMBL14097830 | 0.77 | CYP3A4 (0.54) | CYP3A4LMNAPOLBCYP2D6MAPT | |
| SCHEMBL5014622 | 0.77 | CYP3A4 (0.54) | CYP3A4LMNAPOLBCYP2D6MAPT | |
| Podofilox SCHEMBL1979036 | 0.69 | LMNA (0.77) | CYP3A4LMNAHTTMAPTGAA | |
| SCHEMBL9951919 | 0.69 | GSK3B (0.47) | CYP3A4LMNAPOLBCYP2D6ATM | |
| Stegane SCHEMBL5014561 | 0.68 | TUBB4A (0.53) | POLBATMTUBB4ATUBBTUBA3C | |
| Picrostegane SCHEMBL14097820 | 0.68 | TUBB4A (0.53) | POLBATMTUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0843018-B1 | Use of certain amides as probes for detection of antitubulin activity and resistance monitoring | ROHM & HAAS (US) | 2000-07-05 | — | — | EP | disclosed |