Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8045082 | 0.88 | MEN1 (0.45) | HPGDLMNAKDM4ELRRK2DRD2 | |
| SCHEMBL8050800 | 0.87 | HTR1A (0.49) | HPGDLMNAKDM4EHTR1AHTR7 | |
| SCHEMBL8044119 | 0.85 | PTGS2 (0.35) | HPGDLMNAKDM4ELRRK2DRD2 | |
| SCHEMBL8033660 | 0.85 | MAPT (0.44) | HPGDLMNAKDM4EHTR1AHTR7 | |
| SCHEMBL8033982 | 0.84 | KDM4E (0.50) | KDM4ELRRK2DRD2MEN1KMT2A | |
| SCHEMBL8046726 | 0.84 | RAB9A (0.41) | HPGDLMNAKDM4ELRRK2MEN1 | |
| SCHEMBL8048230 | 0.82 | KDM4E (0.43) | HPGDLMNAKDM4EMEN1KMT2A | |
| SCHEMBL8043073 | 0.79 | TSHR (0.42) | HPGDKDM4ELRRK2MEN1KMT2A | |
| SCHEMBL8043614 | 0.78 | DCUN1D1 (0.41) | HTR1AHTR7DRD2HTR2A | |
| SCHEMBL8033827 | 0.78 | TSHR (0.52) | HPGDKDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |