Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TLR5 | O60602 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8047373 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2ATMNPC1LMNATSHR | |
| SCHEMBL8046872 | 0.82 | RPA1 (0.52) | SMN1; SMN2MAPTNPC1LMNATSHR | |
| SCHEMBL8044158 | 0.82 | TSHR (0.54) | SMN1; SMN2MAPTNPC1LMNATSHR | |
| SCHEMBL8041927 | 0.80 | TP53 (0.47) | SMN1; SMN2MAPTNPC1LMNATSHR | |
| SCHEMBL8042069 | 0.79 | LMNA (0.40) | SMN1; SMN2MAPTNPC1LMNATSHR | |
| SCHEMBL8044821 | 0.79 | ALDH1A1 (0.47) | SMN1; SMN2MAPTNPC1LMNATSHR | |
| SCHEMBL8042581 | 0.78 | ATM (0.47) | SMN1; SMN2ATMMAPTNPC1TSHR | |
| SCHEMBL8050159 | 0.78 | LMNA (0.42) | SMN1; SMN2MAPTNPC1LMNATSHR | |
| SCHEMBL8051092 | 0.78 | ATM (0.47) | SMN1; SMN2ATMMAPTNPC1LMNA | |
| SCHEMBL8720215 | 0.76 | HTT (0.48) | SMN1; SMN2MAPTNPC1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |