Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8052290 | 0.94 | GLA (0.44) | ALPGCDC25ACDC25BPTGS2HPGD | |
| SCHEMBL8050964 | 0.90 | ALPG (0.40) | ALPGCDC25ACDC25BPTGS2HPGD | |
| SCHEMBL8033695 | 0.89 | ALPG (0.44) | ALPGCDC25ACDC25BPTGS2HPGD | |
| SCHEMBL8043910 | 0.83 | ALPG (0.46) | ALPGCDC25ACDC25BHPGDMAPT | |
| SCHEMBL8043642 | 0.83 | MAPT (0.52) | ALPGCDC25ACDC25BPTGS2HPGD | |
| SCHEMBL8032745 | 0.82 | MEN1 (0.45) | ALPGCDC25ACDC25BHPGDMAPT | |
| SCHEMBL8709945 | 0.82 | ALDH1A1 (0.52) | HPGDMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL8033784 | 0.81 | ALPG (0.42) | ALPGCDC25ACDC25BPTGS2HPGD | |
| SCHEMBL8041786 | 0.80 | NPSR1 (0.55) | HPGDMAPTALDH1A1RECQLKMT2A | |
| SCHEMBL8032437 | 0.79 | ALPG (0.42) | ALPGCDC25ACDC25BPTGS2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |