Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044539 | 0.90 | ALPG (0.44) | ALPGCDC25ACDC25BRECQLCYP19A1 | |
| SCHEMBL8052290 | 0.85 | GLA (0.44) | ALPGCDC25ACDC25BCYP19A1PTGS2 | |
| SCHEMBL8032500 | 0.85 | ALDH1A1 (0.42) | PTGS2NPSR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8033695 | 0.83 | ALPG (0.44) | ALPGCDC25ACDC25BRECQLCYP19A1 | |
| SCHEMBL8046012 | 0.82 | NPSR1 (0.46) | PTGS2NPSR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8033827 | 0.80 | TSHR (0.52) | RECQLPTGS2NPSR1ALDH1A1KMT2A | |
| SCHEMBL8044252 | 0.79 | ATM (0.41) | ALDH1A1KMT2AHPGDMAPK1EIF4E | |
| SCHEMBL8042871 | 0.78 | TSHR (0.44) | RECQLPTGS2NPSR1ALDH1A1KMT2A | |
| SCHEMBL8044342 | 0.78 | ALPG (0.43) | ALPGCDC25ACDC25BRECQLNPSR1 | |
| SCHEMBL8043910 | 0.78 | ALPG (0.46) | ALPGCDC25ACDC25BNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |