Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CDC25A | P30304 | 2/20 | 0.43 |
| ▸ | CDC25B | P30305 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044539 | 0.94 | ALPG (0.44) | ALPGLMNANPSR1SMN1; SMN2USP2 | |
| SCHEMBL8050964 | 0.85 | ALPG (0.40) | ALPGLMNANPSR1SMN1; SMN2HTT | |
| SCHEMBL8033695 | 0.85 | ALPG (0.44) | ALPGLMNANPSR1SMN1; SMN2TSHR | |
| SCHEMBL8716316 | 0.83 | TP53 (0.54) | GLALMNANPSR1SMN1; SMN2USP2 | |
| SCHEMBL8043910 | 0.80 | ALPG (0.46) | ALPGLMNANPSR1SMN1; SMN2TSHR | |
| SCHEMBL8052217 | 0.79 | LMNA (0.52) | GLAALPGLMNANPSR1SMN1; SMN2 | |
| SCHEMBL8043642 | 0.79 | MAPT (0.52) | ALPGLMNANPSR1SMN1; SMN2USP2 | |
| SCHEMBL8032437 | 0.79 | ALPG (0.42) | GLAALPGLMNANPSR1SMN1; SMN2 | |
| SCHEMBL8032745 | 0.79 | MEN1 (0.45) | ALPGLMNANPSR1SMN1; SMN2TSHR | |
| SCHEMBL8045447 | 0.77 | POLA1 (0.41) | ALPGLMNANPSR1SMN1; SMN2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |