SCHEMBL804454

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2628404	0.93	KDM4E (0.35)	LIMK1PIM3ALDH1A1KDM4EROCK1
	SCHEMBL15317273	0.90	KDM4E (0.37)	LIMK1PIM3ALDH1A1KDM4EROCK1
	SCHEMBL15317344	0.90	LIMK1 (0.34)	LIMK1PIM3KDM4EATML3MBTL1
	SCHEMBL2628340	0.90	KDM4E (0.31)	LIMK1PIM3GPR3ACHEKDM4E
	SCHEMBL9889150	0.90	KDM4E (0.34)	LIMK1PIM3KDM4EROCK1ATM
	SCHEMBL18232902	0.89	LIMK1 (0.37)	LIMK1PIM3ACHEALDH1A1KDM4E
	SCHEMBL18232901	0.89	LIMK1 (0.37)	LIMK1PIM3ACHEALDH1A1KDM4E
	SCHEMBL18232927	0.89	LIMK1 (0.37)	LIMK1PIM3ACHEALDH1A1KDM4E
	SCHEMBL18232855	0.89	LIMK1 (0.37)	LIMK1PIM3ACHEALDH1A1KDM4E
	SCHEMBL15317254	0.89	LIMK1 (0.36)	LIMK1PIM3ALDH1A1KDM4EROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.