Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | NR2E1 | Q9Y466 | 2/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.46 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.46 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RORA | P35398 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL804703 | 0.81 | CYP3A4 (0.74) | CYP3A4NPC1MEN1KMT2A | |
| SCHEMBL379808 | 0.81 | CYP3A4 (0.60) | CYP3A4NR2E1ACLYDNMT1DNMT3L | |
| SCHEMBL804704 | 0.81 | KMT2A (0.52) | CYP3A4NPC1L3MBTL1MEN1KMT2A | |
| SCHEMBL7082250 | 0.80 | NAMPT (0.51) | CYP3A4KDRNR2E1ACLYDNMT1 | |
| SCHEMBL7784318 | 0.76 | DNMT1 (0.65) | CYP3A4KDRNR2E1ACLYDNMT1 | |
| SCHEMBL16302943 | 0.75 | POLB (0.46) | CYP3A4NPC1L3MBTL1MEN1KMT2A | |
| SCHEMBL1304683 | 0.73 | PPARA (0.61) | CYP3A4NPC1MEN1KMT2A | |
| SCHEMBL4601893 | 0.73 | GRM4 (0.62) | NPC1MEN1KMT2A | |
| SCHEMBL16265333 | 0.72 | PPARA (0.54) | CYP3A4NPC1MEN1KMT2A | |
| SCHEMBL804709 | 0.71 | JAK2 (0.54) | CYP3A4NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040553-B2 | Phenoxyisobutyric acid compounds and method of synthesis | Cell Viable Corporation (US) | 2015-05-26 | — | — | US | disclosed |
| US-9040553-B2 | Phenoxyisobutyric acid compounds and method of synthesis | Cell Viable Corporation (US) | 2015-05-26 | — | — | US | disclosed |
| US-20140350045-A1 | PHENOXYISOBUTYRIC ACID COMPOUNDS AND METHOD OF SYNTHESIS | LALEZARI IRAJ (US) | 2014-11-27 | — | — | US | disclosed |
| US-20140350045-A1 | PHENOXYISOBUTYRIC ACID COMPOUNDS AND METHOD OF SYNTHESIS | LALEZARI IRAJ (US) | 2014-11-27 | — | — | US | disclosed |
| US-20120071502-A1 | Novel phenoxyisobutyric acid compounds and methods for synthesis | Cell Viable Corporation (US) | 2012-03-22 | — | — | US | disclosed |
| US-20120071502-A1 | Novel phenoxyisobutyric acid compounds and methods for synthesis | Cell Viable Corporation (US) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350045-A1 | PHENOXYISOBUTYRIC ACID COMPOUNDS AND METHOD OF SYNTHESIS | AGER, BPGM, PDXK | CYP3A4 390/4885NPC1 4742/4885KDR 3604/4885 |
| US-20120071502-A1 | Novel phenoxyisobutyric acid compounds and methods for synthesis | AGER, BPGM, PDXK | CYP3A4 1030/4885NPC1 4737/4885KDR 3317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.