Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044755 | 0.75 | CRHR1 (0.43) | S1PR4LMNAVCAM1POLB | |
| SCHEMBL8809905 | 0.72 | LMNA (0.45) | MAPTKDM4EBLMTDP1HTT | |
| SCHEMBL29672031 | 0.71 | ALDH1A1 (0.50) | MAPTTDP1HTTS1PR4LMNA | |
| SCHEMBL29779688 | 0.71 | ALDH1A1 (0.47) | MAPTTDP1HTTLMNATSHR | |
| SCHEMBL563664 | 0.71 | ALDH1A1 (0.50) | MAPTTDP1HTTS1PR4LMNA | |
| SCHEMBL1625178 | 0.71 | ALDH1A1 (0.47) | MAPTTDP1HTTLMNATSHR | |
| SCHEMBL23530034 | 0.69 | NR4A2 (0.43) | MAPTTDP1HTTLMNAALDH1A1 | |
| SCHEMBL5844440 | 0.68 | CRHR1 (0.43) | MAPT | |
| SCHEMBL20595552 | 0.68 | ALDH1A1 (0.45) | MAPTTDP1HTTLMNATSHR | |
| SCHEMBL30014602 | 0.68 | ALDH1A1 (0.45) | MAPTTDP1HTTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107301-A | PSYCHOLOGICAL DISORDERS | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-08-22 | — | — | US | disclosed |