Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 14/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5844440 | 0.78 | CRHR1 (0.43) | CRHR1 | |
| SCHEMBL8044751 | 0.75 | MAPT (0.33) | VCAM1POLBLMNAS1PR4 | |
| SCHEMBL2549528 | 0.74 | LMNA (0.52) | POLBLMNASMN1; SMN2 | |
| SCHEMBL8809905 | 0.71 | LMNA (0.45) | POLBLMNAS1PR4 | |
| SCHEMBL563664 | 0.70 | ALDH1A1 (0.50) | POLBLMNASMN1; SMN2S1PR4 | |
| SCHEMBL29779688 | 0.70 | ALDH1A1 (0.47) | POLBLMNASMN1; SMN2 | |
| SCHEMBL29672031 | 0.70 | ALDH1A1 (0.50) | POLBLMNASMN1; SMN2S1PR4 | |
| SCHEMBL1625178 | 0.70 | ALDH1A1 (0.47) | POLBLMNASMN1; SMN2 | |
| SCHEMBL7224417 | 0.69 | LMNA (0.33) | POLBLMNAS1PR4 | |
| SCHEMBL7222310 | 0.69 | LMNA (0.33) | POLBLMNAS1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107301-A | PSYCHOLOGICAL DISORDERS | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-08-22 | — | — | US | disclosed |