Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPA1 | P27694 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | EIF4E | P06730 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8052292 | 0.89 | RPA1 (0.46) | RPA1TSHRALDH1A1MAPK1KDM4E | |
| SCHEMBL8033827 | 0.87 | TSHR (0.52) | TSHRALDH1A1MAPK1KDM4EHSD17B10 | |
| SCHEMBL8042745 | 0.84 | RPA1 (0.47) | RPA1TSHRALDH1A1MAPK1KDM4E | |
| SCHEMBL8044252 | 0.82 | ATM (0.41) | TSHRALDH1A1MAPK1KDM4EEIF4E | |
| SCHEMBL8042687 | 0.80 | RPA1 (0.48) | RPA1TSHRALDH1A1MAPK1KDM4E | |
| SCHEMBL8032690 | 0.80 | KDM4E (0.45) | TSHRALDH1A1KDM4EHSD17B10EIF4E | |
| SCHEMBL8032500 | 0.80 | ALDH1A1 (0.42) | TSHRALDH1A1MAPK1KDM4EHSD17B10 | |
| SCHEMBL8042871 | 0.80 | TSHR (0.44) | TSHRALDH1A1MAPK1KDM4EHSD17B10 | |
| SCHEMBL8051011 | 0.79 | EIF4E (0.35) | TSHRALDH1A1MAPK1KDM4EHSD17B10 | |
| SCHEMBL8051217 | 0.79 | EIF4E (0.36) | TSHRALDH1A1KDM4EHSD17B10EIF4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |