Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPA1 | P27694 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042745 | 0.93 | RPA1 (0.47) | RPA1TSHRKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL8044765 | 0.89 | RPA1 (0.41) | RPA1TSHRKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL8042687 | 0.87 | RPA1 (0.48) | RPA1TSHRKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL8046211 | 0.84 | RPA1 (0.48) | RPA1TSHRKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL8049124 | 0.82 | TSHR (0.60) | TSHRKDM4EHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL8044879 | 0.82 | RPA1 (0.47) | RPA1TSHRKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL8042821 | 0.81 | RPA1 (0.54) | RPA1TSHRKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL8033921 | 0.80 | RPA1 (0.47) | RPA1TSHRKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL8049440 | 0.79 | RPA1 (0.51) | RPA1TSHRKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL8032636 | 0.78 | ATM (0.47) | TSHRALDH1A1MAPK1HDAC6HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |