SCHEMBL1156874

SCHEMBL1156874

[CH2]CSc1cccc2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IFNAR1 P17181 1/20 0.43
ALDH1A1 P00352 5/20 0.42
LMNA P02545 2/20 0.42
MAPK1 P28482 2/20 0.42
NPY1R P25929 1/20 0.42
NPY2R P49146 1/20 0.42
CYP1A2 P05177 3/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
HDAC3 O15379 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC10 Q969S8 1/20 0.42
HDAC11 Q96DB2 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
HDAC9 Q9UKV0 1/20 0.42
HDAC5 Q9UQL6 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8038665 0.83 IFNAR1 (0.41) IFNAR1ALDH1A1LMNAMAPK1NPY1R
SCHEMBL8044798 0.80 IFNAR1 (0.39) IFNAR1ALDH1A1LMNAMAPK1NPY1R
SCHEMBL1057367 0.78 IFNAR1 (0.47) IFNAR1ALDH1A1LMNAMAPK1NPY1R
SCHEMBL17058596 0.78 IFNAR1 (0.43) IFNAR1ALDH1A1LMNAMAPK1NPY1R
SCHEMBL6293960 0.78 IFNAR1 (0.43) IFNAR1ALDH1A1LMNAMAPK1NPY1R
SCHEMBL2399229 0.78 HDAC3 (0.45) IFNAR1ALDH1A1LMNAMAPK1NPY1R
SCHEMBL2232580 0.78 HDAC3 (0.45) IFNAR1ALDH1A1LMNAMAPK1NPY1R
SCHEMBL2607720 0.78 L3MBTL1 (0.50) IFNAR1ALDH1A1LMNAMAPK1NPY1R
SCHEMBL2117027 0.78 IFNAR1 (0.44) IFNAR1ALDH1A1LMNAMAPK1NPY1R
SCHEMBL5071846 0.77 IFNAR1 (0.37) IFNAR1ALDH1A1LMNAMAPK1NPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220119567-A1 NETWORK POLYMERS AND METHODS OF MAKING AND USING SAME NATIONAL SCIENCE FOUNDATION 2022-04-21 US claimed
WO-2021012700-A1 COMPOUND FOR ENCAPSULATION FILM AND COMPOSITION THEREOF, AND FILM, ORGANIC LIGHT-EMITTING DEVICE AND ENCAPSULATION METHOD 吉林奥来德光电材料股份有限公司 2021-01-28 WO claimed
CN-106366324-B Hyperbranched polymer coated nano-particle, preparation method thereof, brightness enhancement composition containing hyperbranched polymer coated nano-particle, brightness enhancement film and LED display 张家港康得新光电材料有限公司 2020-03-03 CN claimed
US-20110043727-A1 ADHESIVE LAYER FOR MULTILAYER OPTICAL FILM 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-02-24 US claimed
EP-2263112-A2 ADHESIVE LAYER FOR MULTILAYER OPTICAL FILM 3M Innovative Properties Company (US) 2010-12-22 EP claimed
WO-2009145939-A1 ADHESIVE LAYER FOR MULTILAYER OPTICAL FILM 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-12-03 WO claimed
WO-2009145998-A2 ADHESIVE LAYER FOR MULTILAYER OPTICAL FILM 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-12-03 WO claimed
US-20070082988-A1 Compositions for articles comprising replicated microstructures GENERAL ELECTRIC COMPANY (US) 2007-04-12 US claimed
US-7192983-B2 Improving storage stability by reacting with hydrogen sulfate lithium- containing compound; aspartyl protease inhibitors G.D. SEARLE & CO. (US) 2007-03-20 US claimed
US-20060128853-A1 Compositions for articles comprising replicated microstructures GENERAL ELECTRIC COMPANY (US) 2006-06-15 US claimed
US-20060074247-A1 N-protected/N-substituted-beta-amino hydroxy sulfonates G.D. SEARLE & CO. (US) 2006-04-06 US claimed
US-6586627-B1 Blocking carbocyclic oxo, amines such as 2-(bis(phenylmethyl) amino)-3-phenylpropanal to form 2-(Bis(phenylmethyl)amino)-1-hydroxy-3-phenylpropylsulfonic Acid Salts, having storage stability; chemical intermediates for enzyme inhibitors G. D. SEARLE & CO. 2003-07-01 US claimed
WO-2000079312-A1 HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS BAUSCH & LOMB SURGICAL, INC. (US) 2000-12-28 WO claimed
US-6147253-A STABILIZED FORM OF N-PROTECTED/N-SUBSTITUTED ALPHA-AMINO ALDEHYDES G. D. SEARLE & CO. (US) 2000-11-14 US claimed
EP-0861233-B1 N-PROTECTED/N-SUBSTITUTED-BETA-AMINO HYDROXY SULFONATES SEARLE & CO (US) 2000-05-03 EP claimed
US-5939587-A DEBLOCKING, DESALTING, DESULFONATING AND OXIDATING TO ALDEHYDE; STORAGE STABILITY, MATERIALS HANDLING G. D. SEARLE & COMPANY (US) 1999-08-17 US claimed
US-5847201-A N-protected/N-substituted-beta-amino hydroxy sulfonates G.D. SEARLE & CO. (US) 1998-12-08 US claimed
EP-0861233-A1 N-PROTECTED/N-SUBSTITUTED-BETA-AMINO HYDROXY SULFONATES G.D. SEARLE & CO. (US) 1998-09-02 EP claimed
EP-0804428-A1 BIS-SULFONAMIDE HYDROXYETHYLAMINO RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1997-11-05 EP claimed
WO-1997018190-A1 N-PROTECTED/N-SUBSTITUTED-BETA-AMINO HYDROXY SULFONATES G.D. SEARLE & CO. (US) 1997-05-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060074247-A1 N-protected/N-substituted-beta-amino hydroxy sulfonates AANAT, AASDHPPT, ALDH7A1 IFNAR1 1570/4885ALDH1A1 30/4885LMNA 442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.