Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | IGF1R | P08069 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.52 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.52 |
| ▸ | HTR3B | O95264 | 1/20 | 0.52 |
| ▸ | HTR3A | P46098 | 1/20 | 0.52 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.52 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1803684 | 0.93 | IGF1R (0.59) | L3MBTL1IGF1RALOX15TAAR1HTR3E | |
| SCHEMBL15353394 | 0.91 | IGF1R (0.57) | L3MBTL1IGF1RALOX15TAAR1HTR3E | |
| SCHEMBL15352421 | 0.91 | IGF1R (0.57) | L3MBTL1IGF1RALOX15TAAR1HTR3E | |
| SCHEMBL15352496 | 0.91 | IGF1R (0.57) | L3MBTL1IGF1RALOX15TAAR1HTR3E | |
| SCHEMBL15353436 | 0.91 | IGF1R (0.57) | L3MBTL1IGF1RALOX15TAAR1HTR3E | |
| SCHEMBL1047898 | 0.91 | IGF1R (0.57) | L3MBTL1IGF1RALOX15TAAR1HTR3E | |
| SCHEMBL11207538 | 0.91 | IGF1R (0.57) | L3MBTL1IGF1RALOX15TAAR1HTR3E | |
| SCHEMBL16467667 | 0.91 | IGF1R (0.57) | L3MBTL1IGF1RALOX15TAAR1HTR3E | |
| SCHEMBL1043274 | 0.91 | IGF1R (0.57) | L3MBTL1IGF1RALOX15TAAR1HTR3E | |
| SCHEMBL2759037 | 0.88 | L3MBTL1 (0.47) | L3MBTL1IGF1RALOX15TAAR1HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 254 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240147998-A1 | HERBICIDAL COMPOSITIONS COMPRISING IMIDAZOLINONE-BASED ACETOLACTATE SYNTHASE INHIBITORS AND USES THEREOF | ADAMA AGAN LTD. (IL) | 2024-05-09 | — | — | US | claimed |
| CN-116640104-B | Industrial synthesis method of telithromycin | 杭州科耀医药科技有限公司 | 2024-04-02 | — | — | CN | claimed |
| US-11945788-B2 | Process for preparing pitolisant hydrochloride and solid-state forms thereof | NURAY CHEMICALS PRIVATE LIMITED (IN) | 2024-04-02 | — | — | US | claimed |
| CN-116887675-A | Herbicidal compositions comprising imidazolinone-based acetolactate synthase inhibitors and uses thereof | 安道麦阿甘有限公司 | 2023-10-13 | — | — | CN | claimed |
| CN-116640104-A | Industrial synthesis method of telithromycin | 杭州科耀医药科技有限公司 | 2023-08-25 | — | — | CN | claimed |
| US-20230219914-A1 | PROCESS FOR PREPARING PITOLISANT HYDROCHLORIDE AND SOLID-STATE FORMS THEREOF | Nuray Chemicals Private Limiited (IN) | 2023-07-13 | — | — | US | claimed |
| US-20220402886-A1 | PROCESS FOR PREPARING PITOLISANT HYDROCHLORIDE AND SOLID-STATE FORMS THEREOF | Nuray Chemicals Private Lmiited (IN) | 2022-12-22 | — | — | US | claimed |
| WO-2022180626-A1 | HERBICIDAL COMPOSITIONS COMPRISING IMIDAZOLINONE-BASED ACETOLACTATE SYNTHASE INHIBITORS AND USES THEREOF | ADAMA AGAN LTD. (IL) | 2022-09-01 | — | — | WO | claimed |
| CN-110804026-B | Synthesis method of 1- (3- (3- (4-chlorphenyl) propoxy) propyl) piperidine hydrochloride | 苏州永健生物医药有限公司 | 2022-04-01 | — | — | CN | claimed |
| WO-2021023634-A1 | PROCESS FOR THE SYNTHESIS OF PITOLISANT HCl | PROCOS S.P.A. (IT) | 2021-02-11 | — | — | WO | claimed |
| US-20080255120-A1 | SUBSTITUTED 2,5-HETEROCYCLIC DERIVATIVES | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2008-10-16 | — | — | US | claimed |
| EP-1663962-A4 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISEASE ASSOCIATED WITH TRP-P8 EXPRESSION | DENDREON CORP (US) | 2007-08-22 | — | — | EP | claimed |
| JP-2007503392-A | — | — | 2007-02-22 | — | — | JP | claimed |
| EP-1663962-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISEASE ASSOCIATED WITH TRP-P8 EXPRESSION | DENDREON CORPORATION (US) | 2006-06-07 | — | — | EP | claimed |
| US-20050256121-A1 | e.g. 3-(4-fluorophenyl)-N-{5-[2-(methylamino)pyrimidin-4-yl]thien-2-yl}propanamide; PKB/Akt kinase inhibitor; anticarcinogenic agent; carcinoma, cancer metastases, squamous cell carcinoma, esophageal squamous cell carcinoma, oral carcinoma, cutaneous T cell lymphoma, Hodgkin's lymphoma | CHIRON CORPORATION (US) | 2005-11-17 | — | — | US | claimed |
| US-20050054651-A1 | Compositions and methods for the treatment of disease associated with Trp-p8 expression | DENDREON CORPORATION (US) | 2005-03-10 | — | — | US | claimed |
| WO-2005020897-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISEASE ASSOCIATED WITH TRP-P8 EXPRESSION | DENDREON CORPORATION (US) | 2005-03-10 | — | — | WO | claimed |
| EP-0443560-A2 | HIV protease inhibitors | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1991-08-28 | — | — | EP | claimed |
| EP-0443573-A2 | HIV protease inhibitors containing derived amino acids | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1991-08-28 | — | — | EP | claimed |
| US-4474748-A | ANTIBIOTICS, FUNGICIDES, ANTISEPTICS | JOHNSON & JOHNSON (US) | 1984-10-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220402886-A1 | PROCESS FOR PREPARING PITOLISANT HYDROCHLORIDE AND SOLID-STATE FORMS THEREOF | PITHD1, MLN, TPP1 | L3MBTL1 3511/4885IGF1R 2867/4885ALOX15 3558/4885 |
| US-11945788-B2 | Process for preparing pitolisant hydrochloride and solid-state forms thereof | PITHD1, MLN, TPP1 | L3MBTL1 3511/4885IGF1R 2867/4885ALOX15 3558/4885 |
| US-20050256121-A1 | e.g. 3-(4-fluorophenyl)-N-{5-[2-(methylamino)pyrimidin-4-yl]thien-2-yl}propanamide; PKB/Akt kinase inhibitor; anticarcinogenic agent; carcinoma, cancer metastases, squamous cell carcinoma, esophageal squamous cell carcinoma, oral carcinoma, cutaneous T cell lymphoma, Hodgkin's lymphoma | MALT1, AKT1, PIK3CA | L3MBTL1 3021/4885IGF1R 1010/4885ALOX15 3443/4885 |
| US-20240147998-A1 | HERBICIDAL COMPOSITIONS COMPRISING IMIDAZOLINONE-BASED ACETOLACTATE SYNTHASE INHIBITORS AND USES THEREOF | PPOX, ACOX1, PAOX | L3MBTL1 1454/4885IGF1R 982/4885ALOX15 15/4885 |
| US-20230219914-A1 | PROCESS FOR PREPARING PITOLISANT HYDROCHLORIDE AND SOLID-STATE FORMS THEREOF | PITHD1, MLN, TPP1 | L3MBTL1 3511/4885IGF1R 2867/4885ALOX15 3558/4885 |
| US-20080255120-A1 | SUBSTITUTED 2,5-HETEROCYCLIC DERIVATIVES | CYP3A5, ABCG2, ABCB1 | L3MBTL1 4814/4885IGF1R 2308/4885ALOX15 2944/4885 |
| US-20050054651-A1 | Compositions and methods for the treatment of disease associated with Trp-p8 expression | TRPC4, TRPC3, TRPC1 | L3MBTL1 1910/4885IGF1R 4134/4885ALOX15 2356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.