Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8046949 | 0.82 | L3MBTL1 (0.38) | L3MBTL1KDM4C | |
| SCHEMBL8045648 | 0.78 | L3MBTL1 (0.35) | L3MBTL1 | |
| SCHEMBL8046730 | 0.77 | MLNR (0.32) | — | |
| SCHEMBL27456756 | 0.72 | KDM4E (0.31) | — | |
| SCHEMBL10508354 | 0.66 | CA2 (0.38) | L3MBTL1KDM4C | |
| SCHEMBL26126355 | 0.66 | CYP1A2 (0.37) | L3MBTL1KDM4C | |
| SCHEMBL283701 | 0.66 | CYP1A2 (0.37) | L3MBTL1KDM4C | |
| SCHEMBL27374326 | 0.63 | NFKB1 (0.31) | — | |
| SCHEMBL25366018 | 0.62 | L3MBTL1 (0.32) | L3MBTL1 | |
| SCHEMBL10506002 | 0.62 | PRMT5 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100268-A | MIGRAINES | JANSSEN PHARMACEUTICA, N.V. (BE) | 2000-08-08 | — | — | US | disclosed |
| EP-0714396-A1 | VASOCONTRICTIVE DIHYDROBENZOPYRAN DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995005383-A1 | VASOCONTRICTIVE DIHYDROBENZOPYRAN DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1995-02-23 | — | — | WO | disclosed |