Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8046949 | 0.82 | L3MBTL1 (0.38) | L3MBTL1 | |
| SCHEMBL8044902 | 0.78 | L3MBTL1 (0.35) | L3MBTL1 | |
| SCHEMBL8046921 | 0.77 | PIN1 (0.35) | — | |
| SCHEMBL10506002 | 0.75 | PRMT5 (0.35) | MEN1KMT2A | |
| SCHEMBL27347850 | 0.72 | RAB9A (0.35) | — | |
| SCHEMBL26126355 | 0.68 | CYP1A2 (0.37) | L3MBTL1MEN1KMT2A | |
| SCHEMBL283701 | 0.68 | CYP1A2 (0.37) | L3MBTL1MEN1KMT2A | |
| SCHEMBL8052477 | 0.67 | PIN1 (0.37) | L3MBTL1HCAR3 | |
| SCHEMBL31317363 | 0.67 | ALDH1A1 (0.38) | L3MBTL1MEN1KMT2AHCAR3 | |
| SCHEMBL20985435 | 0.66 | ALDH1A1 (0.38) | L3MBTL1MEN1KMT2AHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100268-A | MIGRAINES | JANSSEN PHARMACEUTICA, N.V. (BE) | 2000-08-08 | — | — | US | disclosed |
| EP-0714396-A1 | VASOCONTRICTIVE DIHYDROBENZOPYRAN DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995005383-A1 | VASOCONTRICTIVE DIHYDROBENZOPYRAN DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1995-02-23 | — | — | WO | disclosed |