Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10353198 | 0.73 | ALPI (0.56) | PKM | |
| Bromide SCHEMBL10353196 | 0.72 | ALPI (0.54) | PKM | |
| SCHEMBL15781198 | 0.72 | LMNA (0.43) | MAPK1SMN1; SMN2L3MBTL1POLBPKM | |
| SCHEMBL15768221 | 0.72 | LMNA (0.43) | MAPK1SMN1; SMN2L3MBTL1POLBPKM | |
| SCHEMBL6996344 | 0.71 | CHRM1 (0.51) | SMN1; SMN2L3MBTL1HIF1APKMLMNA | |
| SCHEMBL9522165 | 0.69 | SRC (0.53) | MAPK1SMN1; SMN2L3MBTL1HIF1APKM | |
| SCHEMBL28651090 | 0.69 | THRB (0.40) | MAPK1SMN1; SMN2L3MBTL1POLBPKM | |
| SCHEMBL10458711 | 0.69 | ANPEP (0.41) | ALDH1A1 | |
| SCHEMBL9038953 | 0.68 | GRIN2D (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL10769502 | 0.68 | MMP8 (0.43) | MAPK1SMN1; SMN2L3MBTL1HIF1APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001969-A1 | PEPTIDOMIMETIC DERIVATIVES SUICIDAL INHIBITORS OF THE HIV PROLIFERATION | ZAMBON GROUP S.p.A. (IT) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999001470-A2 | PEPTIDOMIMETIC DERIVATIVES SUICIDAL INHIBITORS OF THE HIV PROLIFERATION | ZAMBON GROUP S.P.A. (IT) | 1999-01-14 | — | — | WO | disclosed |