Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 5/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8050257 | 0.92 | ALDH1A1 (0.42) | ALDH1A1LMNAHTR2ACARM1PRMT6 | |
| SCHEMBL8044366 | 0.88 | HTR1A (0.46) | — | |
| SCHEMBL8863957 | 0.87 | HTR1A (0.46) | — | |
| SCHEMBL5723845 | 0.80 | HTR1A (0.43) | — | |
| SCHEMBL8047887 | 0.80 | MAOB (0.57) | — | |
| SCHEMBL8053417 | 0.79 | SIGMAR1 (0.47) | — | |
| SCHEMBL8046689 | 0.77 | MAOB (0.55) | ALDH1A1LMNA | |
| SCHEMBL8048207 | 0.76 | SIGMAR1 (0.45) | ALDH1A1LMNA | |
| SCHEMBL8053395 | 0.75 | SIGMAR1 (0.58) | — | |
| SCHEMBL8787321 | 0.74 | APP (0.43) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0679649-B1 | 2,3-Dihydrobenzofuran Derivatives | ASAHI CHEMICAL IND (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5792791-A | FOR PREVENTION AND TREATMENT OF SEROTONERGIC NEURON-RELATED DISEASES; HYPOTENSIVE AGENTS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1998-08-11 | — | — | US | disclosed |
| EP-0769496-A1 | NOVEL 2,3-DIHYDROBENZOFURAN DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1997-04-23 | — | — | EP | disclosed |
| EP-0679649-A1 | 2,3-DIHYDROBENZOFURAN DERIVATIVE | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1995-11-02 | — | — | EP | disclosed |