Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 9/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8053417 | 0.94 | SIGMAR1 (0.47) | SIGMAR1TMEM97NPC1RAB9AOPRM1 | |
| SCHEMBL8036049 | 0.93 | TMEM97 (0.52) | SIGMAR1TMEM97NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8047459 | 0.91 | NPC1 (0.49) | SIGMAR1TMEM97NPC1HPGDRAB9A | |
| SCHEMBL8053395 | 0.87 | SIGMAR1 (0.58) | SIGMAR1TMEM97NPC1RAB9AOPRM1 | |
| SCHEMBL8787114 | 0.85 | ALDH1A1 (0.41) | SIGMAR1TMEM97NPC1HPGDALDH1A1 | |
| SCHEMBL8053562 | 0.82 | HPGD (0.42) | SIGMAR1TMEM97NPC1HPGDRAB9A | |
| SCHEMBL8035853 | 0.81 | DRD2 (0.48) | SIGMAR1TMEM97NPC1HPGDRAB9A | |
| SCHEMBL8036154 | 0.81 | SIGMAR1 (0.47) | SIGMAR1TMEM97NPC1HPGDRAB9A | |
| SCHEMBL8787321 | 0.80 | APP (0.43) | SIGMAR1TMEM97HPGDALDH1A1LMNA | |
| SCHEMBL8045249 | 0.80 | TMEM97 (0.48) | SIGMAR1TMEM97NPC1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0679649-B1 | 2,3-Dihydrobenzofuran Derivatives | ASAHI CHEMICAL IND (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5792791-A | FOR PREVENTION AND TREATMENT OF SEROTONERGIC NEURON-RELATED DISEASES; HYPOTENSIVE AGENTS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1998-08-11 | — | — | US | disclosed |
| EP-0679649-A1 | 2,3-DIHYDROBENZOFURAN DERIVATIVE | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1995-11-02 | — | — | EP | disclosed |