Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044769 | 0.96 | GAA (0.39) | CCR1GAAHDAC6HDAC3HDAC4 | |
| SCHEMBL8045183 | 0.94 | OPRM1 (0.43) | CCR1OPRM1CYP2D6DRD2DRD4 | |
| SCHEMBL8044965 | 0.94 | OPRM1 (0.43) | CCR1OPRM1CYP2D6DRD2DRD4 | |
| SCHEMBL8050105 | 0.86 | HDAC3 (0.38) | OPRM1KCNA3GAAHDAC6HDAC3 | |
| SCHEMBL8035617 | 0.85 | KMT2A (0.40) | CCR1CYP3A4CYP2C9KCNH2GAA | |
| SCHEMBL8035359 | 0.84 | ALDH1A1 (0.41) | CCR1HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL8052916 | 0.83 | HDAC6 (0.41) | CCR1CYP2D6CYP3A4CYP2C9KCNH2 | |
| SCHEMBL8045870 | 0.82 | HDAC6 (0.49) | CCR1CYP3A4KCNH2HDAC6HDAC3 | |
| SCHEMBL8047298 | 0.82 | OPRM1 (0.44) | CCR1OPRM1CYP2D6DRD2DRD4 | |
| SCHEMBL8044945 | 0.81 | KCNA3 (0.41) | CCR1OPRM1CYP2D6DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749957-B1 | Aromatic hydroxamic acid compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5891916-A | ANTINEUROGEGERATIVE AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0749957-A1 | Aromatic hydroxamic acid compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1996-12-27 | — | — | EP | disclosed |