Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | QPCT | Q16769 | 1/20 | 0.38 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8048610 | 0.87 | ALDH1A1 (0.46) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL8031756 | 0.80 | FBP1 (0.44) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL8032711 | 0.80 | FBP1 (0.40) | HSD17B10FBP1PDK1 | |
| SCHEMBL8043809 | 0.78 | FBP1 (0.42) | MEN1KMT2APOLBALDH1A1HSD17B10 | |
| SCHEMBL8032531 | 0.78 | APEX1 (0.37) | ALDH1A1SMN1; SMN2PLA2G4AFBP1PDK1 | |
| SCHEMBL8044890 | 0.77 | ATM (0.47) | ATMRAB9ANPC1MEN1KMT2A | |
| SCHEMBL8043927 | 0.77 | ATM (0.47) | ATMRAB9ANPC1MEN1KMT2A | |
| SCHEMBL8045096 | 0.77 | PDPK1 (0.51) | ATMNPC1MEN1KMT2APOLB | |
| SCHEMBL8048705 | 0.76 | FBP1 (0.46) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL8046775 | 0.76 | FBP1 (0.42) | ALDH1A1FBP1PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |