Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | EIF4E | P06730 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049863 | 0.90 | MAPT (0.43) | MAPTLMNAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8041970 | 0.83 | EIF4E (0.40) | MAPTLMNAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8043194 | 0.83 | KMT2A (0.43) | MAPTLMNAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8046358 | 0.83 | LMNA (0.39) | MAPTLMNAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8047853 | 0.81 | KMT2A (0.40) | MAPTLMNAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8710052 | 0.79 | LMNA (0.41) | KDM1AMAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8047667 | 0.78 | LMNA (0.40) | KDM1AMAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8046591 | 0.77 | ALDH1A1 (0.39) | MAPTLMNAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8043842 | 0.77 | KMT2A (0.44) | MAPTLMNAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8043591 | 0.77 | KMT2A (0.37) | MAPTLMNAALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |