Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2138396 | 0.82 | DRD1 (0.59) | DRD1ACERIPK1MTNR1BCYP2D6 | |
| SCHEMBL337653 | 0.75 | CTSB (0.37) | ALDH1A1 | |
| SCHEMBL11387535 | 0.75 | CTSB (0.37) | ALDH1A1 | |
| SCHEMBL9873974 | 0.74 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL9508172 | 0.73 | DRD1 (0.57) | DRD1ACERIPK1MTNR1BCYP2D6 | |
| SCHEMBL5603396 | 0.69 | CTSB (0.32) | ALDH1A1 | |
| SCHEMBL9873835 | 0.69 | CTSB (0.32) | ALDH1A1 | |
| SCHEMBL18711615 | 0.69 | DRD1 (0.60) | DRD1ACERIPK1MTNR1BSMN1; SMN2 | |
| SCHEMBL10312392 | 0.69 | DRD1 (0.60) | DRD1ACERIPK1MTNR1BSMN1; SMN2 | |
| SCHEMBL9875395 | 0.68 | ALDH1A1 (0.39) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802732-B1 | HERBICIDAL COMPOSITIONS OF 4-BENZOYLISOXAZOLE OR 2-CYANO-1,3-DIONE HERBICIDES AND ANTIDOTES THEREFOR | ZENECA LTD (GB) | 2000-04-19 | — | — | EP | disclosed |