Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038929 | 0.84 | KEAP1 (0.32) | ELANE | |
| SCHEMBL9834843 | 0.80 | ESR1 (0.37) | ELANE | |
| SCHEMBL8038860 | 0.80 | ESR1 (0.37) | ELANE | |
| SCHEMBL9698199 | 0.79 | ELANE (0.31) | ELANE | |
| SCHEMBL8039606 | 0.78 | ELANE (0.32) | ELANE | |
| SCHEMBL8976102 | 0.78 | ELANE (0.32) | ELANE | |
| SCHEMBL9428111 | 0.77 | ELANE (0.36) | SMN1; SMN2ELANEMEN1KMT2A | |
| SCHEMBL9427855 | 0.77 | CACNA1C (0.36) | — | |
| SCHEMBL9428941 | 0.77 | CACNA1C (0.36) | — | |
| SCHEMBL8839225 | 0.77 | ELANE (0.31) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587436-B1 | Process for preparing carbapenem and penem compounds and new compounds involved in that process | SANKYO CO (JP) | 2000-05-10 | — | — | EP | disclosed |
| US-5614624-A | THIO SUBSTITUTED, ANTIBIOTICS, CHEMICAL INTERMEDIATES | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| US-5541317-A | PENICILLIN DERIVATIVES, CYCLIZATION OF ESTERS OR THIOESTERS | SANKYO COMPANY, LIMITED (JP) | 1996-07-30 | — | — | US | disclosed |
| EP-0587436-A1 | Process for preparing carbapenem and penem compounds and new compounds involved in that process | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |