Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 5/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP4B1 | P13584 | 2/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.46 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.46 |
| ▸ | CYP2A7 | P20853 | 2/20 | 0.46 |
| ▸ | CYP3A7 | P24462 | 2/20 | 0.46 |
| ▸ | CYP2F1 | P24903 | 2/20 | 0.46 |
| ▸ | CYP2C18 | P33260 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2J2 | P51589 | 2/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.46 |
| ▸ | CYP4F8 | P98187 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27990527 | 0.83 | RAB9A (0.52) | ALDH1A1KDM4ESMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL13401040 | 0.81 | KDM4E (0.64) | ALDH1A1KDM4ESMN1; SMN2KMT2AHPGD | |
| SCHEMBL14557095 | 0.80 | SNCA (0.37) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL23292523 | 0.78 | KDM4E (0.69) | CYP1A1CYP1B1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8043047 | 0.74 | ALDH1A1 (0.51) | CYP1A2CYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL7161310 | 0.74 | HRH3 (0.46) | CYP1A1CYP1B1CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL8050989 | 0.71 | ALDH1A1 (0.60) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL969945 | 0.71 | PIK3CA (0.40) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL14557099 | 0.71 | KDM4E (0.43) | ALDH1A1KDM4ESMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL23292558 | 0.70 | RAB9A (0.57) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |