SCHEMBL13401040

SCHEMBL13401040

COc1ccc(-c2nnc(S)s2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.64
MAPT P10636 3/20 0.64
ALDH1A1 P00352 3/20 0.64
TP53 P04637 2/20 0.64
HSD17B10 Q99714 2/20 0.64
RAB9A P51151 5/20 0.62
NPC1 O15118 3/20 0.62
SMN1; SMN2 Q16637 3/20 0.62
KMT2A Q03164 1/20 0.54
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA4 P22748 1/20 0.53
CA5A P35218 1/20 0.53
CA5B Q9Y2D0 1/20 0.53
HRH3 Q9Y5N1 3/20 0.52
GUSB P08236 1/20 0.48
APP P05067 1/20 0.47
CSNK2A2 P19784 1/20 0.47
CSNK2A1 P68400 1/20 0.47
PKM P14618 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6663651 0.86 KDM4E (0.75) KDM4EMAPTALDH1A1TP53HSD17B10
SCHEMBL14557099 0.84 KDM4E (0.43) KDM4EMAPTALDH1A1TP53HSD17B10
SCHEMBL8046027 0.81 CYP1A1 (0.46) KDM4EMAPTALDH1A1TP53HSD17B10
SCHEMBL9342320 0.81 KDM4E (0.68) KDM4EMAPTALDH1A1TP53HSD17B10
SCHEMBL27990527 0.80 RAB9A (0.52) KDM4EMAPTALDH1A1HSD17B10RAB9A
SCHEMBL13912997 0.79 KDM4E (0.66) KDM4EMAPTALDH1A1TP53HSD17B10
SCHEMBL8050326 0.79 MGAM (0.48) KDM4EMAPTALDH1A1TP53HSD17B10
SCHEMBL8050989 0.79 ALDH1A1 (0.60) KDM4EALDH1A1TP53RAB9ANPC1
SCHEMBL14424574 0.78 RAB9A (0.68) KDM4EMAPTALDH1A1TP53HSD17B10
SCHEMBL1143740 0.78 KDM4E (1.00) KDM4EMAPTALDH1A1TP53HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7695888-B2 Photosensitive lithographic printing plate FUJIFILM CORPORATION (JP) 2010-04-13 US disclosed
US-7695888-B2 Photosensitive lithographic printing plate FUJIFILM CORPORATION (JP) 2010-04-13 US disclosed
US-20070184383-A1 Photosensitive composition, photosensitive planographic printing plate material, and recording method of planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2007-08-09 US disclosed
US-20070184383-A1 Photosensitive composition, photosensitive planographic printing plate material, and recording method of planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2007-08-09 US disclosed