Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | SQOR | Q9Y6N5 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27486706 | 0.85 | PTGS2 (0.38) | PTGS2PTGS1ALDH1A1HPGDPTGDR2 | |
| SCHEMBL1443804 | 0.84 | GRIA1 (0.39) | PTGS2PTGS1ALDH1A1HPGDPTGDR2 | |
| SCHEMBL1343377 | 0.84 | DPP4 (0.56) | ALDH1A1HPGDDPP4HTR7 | |
| SCHEMBL29019013 | 0.82 | TNF (0.47) | ALDH1A1HPGDFFAR1FFAR4DPP4 | |
| SCHEMBL29842617 | 0.82 | TNF (0.47) | ALDH1A1HPGDFFAR1FFAR4DPP4 | |
| SCHEMBL4666102 | 0.81 | ESR2 (0.56) | ALDH1A1HPGDDPP4ADORA1 | |
| SCHEMBL7013171 | 0.81 | HTR7 (0.42) | ALDH1A1HPGDFFAR1FFAR4DPP4 | |
| SCHEMBL554701 | 0.81 | CYP2C19 (0.45) | PTGS2PTGS1ALDH1A1HPGDPTGDR2 | |
| SCHEMBL1041243 | 0.78 | PDK2 (0.49) | PTGS2PTGS1PTGDR2FFAR1FFAR4 | |
| SCHEMBL28812241 | 0.77 | KCNA5 (0.51) | PTGS1ALDH1A1HPGDDPP4SQOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749957-B1 | Aromatic hydroxamic acid compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5891916-A | ANTINEUROGEGERATIVE AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0749957-A1 | Aromatic hydroxamic acid compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1996-12-27 | — | — | EP | disclosed |