Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 7/20 | 0.56 |
| ▸ | MMP3 | P08254 | 3/20 | 0.50 |
| ▸ | ABL1 | P00519 | 2/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.47 |
| ▸ | BCR | P11274 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 5/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1343377 | 0.84 | DPP4 (0.56) | BCL2L1ALDH1A1HPGDDPP4KMT2A | |
| SCHEMBL29842617 | 0.82 | TNF (0.47) | ESR2MMP3ABCB1ALDH1A1HPGD | |
| SCHEMBL29019013 | 0.82 | TNF (0.47) | ESR2MMP3ABCB1ALDH1A1HPGD | |
| SCHEMBL554701 | 0.81 | CYP2C19 (0.45) | ALDH1A1HPGDDPP4KMT2AMEN1 | |
| SCHEMBL7013171 | 0.81 | HTR7 (0.42) | ESR2ALDH1A1HPGDDPP4KMT2A | |
| SCHEMBL8046052 | 0.81 | PTGS2 (0.41) | ALDH1A1HPGDDPP4ADORA1 | |
| SCHEMBL28393638 | 0.80 | ALOX5 (0.53) | ESR2MMP3ABL1ABCB1BCR | |
| SCHEMBL28638330 | 0.79 | ABL1 (0.54) | ESR2MMP3ABL1ABCB1BCR | |
| SCHEMBL3628757 | 0.79 | ABL1 (0.54) | ESR2MMP3ABL1ABCB1BCR | |
| SCHEMBL3556748 | 0.79 | FOLH1 (0.54) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1193250-B1 | PHENYL SULFAMATE DERIVATIVES | TEIKOKU HORMONE MFG CO LTD (JP) | 2008-06-04 | — | — | EP | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |