Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042855 | 0.80 | ALDH1A1 (0.45) | CHRNB4CHRNA3 | |
| SCHEMBL8044837 | 0.68 | — | — | |
| SCHEMBL8044636 | 0.64 | — | — | |
| SCHEMBL993217 | 0.63 | APEX1 (0.44) | CHRNB4CHRNA3 | |
| SCHEMBL8051368 | 0.61 | MAPT (0.37) | — | |
| SCHEMBL8047010 | 0.61 | KIF11 (0.44) | — | |
| Hydrogen Sulfide SCHEMBL11472701 | 0.60 | APEX1 (0.41) | CHRNB4CHRNA3 | |
| SCHEMBL10040717 | 0.60 | APEX1 (0.41) | CHRNB4CHRNA3 | |
| Water SCHEMBL10830901 | 0.60 | APEX1 (0.41) | CHRNB4CHRNA3 | |
| SCHEMBL24617 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |