Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | MPI | P34949 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8046152 | 0.80 | CHRNB4 (0.31) | CHRNB4CHRNA3 | |
| SCHEMBL8047366 | 0.78 | TAAR1 (0.40) | KDM4ERXFP1APOBEC3GMEN1KMT2A | |
| SCHEMBL8041917 | 0.74 | CTSS (0.44) | HSD17B10KDM4ENPC1TSHRMAPK1 | |
| SCHEMBL8033685 | 0.71 | LMNA (0.48) | ALDH1A1GAANPC1TSHRRAB9A | |
| SCHEMBL8046545 | 0.70 | ALOX15 (0.33) | ALDH1A1ALOX15MAPK1 | |
| SCHEMBL312091 | 0.70 | ALDH1A1 (0.52) | ALDH1A1HSD17B10ALOX15HPGDGAA | |
| SCHEMBL29546450 | 0.70 | ALDH1A1 (0.52) | ALDH1A1HSD17B10ALOX15HPGDGAA | |
| SCHEMBL577441 | 0.69 | RAB9A (0.42) | ALDH1A1HSD17B10ALOX15HPGDGAA | |
| SCHEMBL29398919 | 0.67 | ALDH1A1 (0.50) | ALDH1A1HSD17B10ALOX15HPGDGAA | |
| SCHEMBL15624388 | 0.67 | ALDH1A1 (0.50) | ALDH1A1HSD17B10ALOX15HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |