Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 11/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.46 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8046150 | 1.00 | LTA4H (0.53) | LTA4HL3MBTL1LMNAMAPK1CASP3 | |
| SCHEMBL1581041 | 0.86 | GAA (0.53) | L3MBTL1GAAPARP10 | |
| SCHEMBL1581040 | 0.86 | GAA (0.53) | L3MBTL1GAAPARP10 | |
| Hydrochloric Acid SCHEMBL836698 | 0.84 | GAA (0.51) | L3MBTL1GAAPARP10 | |
| SCHEMBL8046227 | 0.79 | WDR5 (0.58) | LTA4HL3MBTL1LMNAMAPK1CASP3 | |
| SCHEMBL17730475 | 0.77 | SLC22A2 (0.53) | LMNASLC22A2PLA2G10PLA2G2ACYP2C9 | |
| SCHEMBL5004504 | 0.75 | ALOX15 (0.70) | LTA4HL3MBTL1LMNAMAPK1CASP3 | |
| SCHEMBL1008238 | 0.75 | SMN1; SMN2 (0.51) | L3MBTL1CYP1A2GAA | |
| SCHEMBL1008237 | 0.75 | SMN1; SMN2 (0.51) | L3MBTL1CYP1A2GAA | |
| SCHEMBL19666875 | 0.75 | MAOB (0.50) | LMNAGAAPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110944-A | AN ANTIINFLAMMATORY AGENT TREATING INFLAMMATORY BOWEL DISEASE | G. D. SEARLE & CO. (US) | 2000-08-29 | — | — | US | disclosed |