SCHEMBL238989

SCHEMBL238989

C=CCc1cc(C(C)(C)c2ccc(OC)c(CC=C)c2)ccc1OC

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 11/20 0.52
GABRB2 P47870 11/20 0.52
ALOX5 P09917 4/20 0.52
CNR2 P34972 2/20 0.52
ALDH1A1 P00352 2/20 0.49
PPARG P37231 1/20 0.49
PPARD Q03181 1/20 0.49
PPARA Q07869 1/20 0.49
PTPN1 P18031 2/20 0.42
CYP3A4 P08684 2/20 0.42
ALOX15 P16050 1/20 0.42
PTGS1 P23219 2/20 0.41
AR P10275 1/20 0.41
TRPM8 Q7Z2W7 1/20 0.41
GABRA5 P31644 1/20 0.40
GABRA3 P34903 1/20 0.40
GABRA2 P47869 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12580079 0.93 GABRA1 (0.47) GABRA1GABRB2ALOX5CNR2ALDH1A1
SCHEMBL10042978 0.91 GABRA1 (0.54) GABRA1GABRB2ALOX5CNR2ALDH1A1
SCHEMBL21277577 0.90 GABRA1 (0.45) GABRA1GABRB2ALOX5CNR2ALDH1A1
SCHEMBL30620383 0.90 GABRA1 (0.52) GABRA1GABRB2ALOX5CNR2ALDH1A1
SCHEMBL804638 0.88 ALOX5 (0.59) GABRA1GABRB2ALOX5CNR2PTPN1
SCHEMBL2456033 0.84 MEN1 (0.48) GABRA1GABRB2ALOX5CNR2ALDH1A1
SCHEMBL29330676 0.83 ALDH1A1 (0.51) GABRA1GABRB2ALOX5CNR2ALDH1A1
SCHEMBL14626463 0.83 GABRA1 (0.38) GABRA1GABRB2ALOX5CNR2ALDH1A1
SCHEMBL16885495 0.83 ELANE (0.40) GABRA1GABRB2ALOX5CNR2ALDH1A1
SCHEMBL29609173 0.83 ELANE (0.40) GABRA1GABRB2ALOX5CNR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4100140-A REACTING POLYMALEIMIDES WITH ALKENYLPHENOLS OR ALKENYLPHENOL ETHERS, POLYMERIZATION CATALYSTS CIBA-GEIGY CORPORATION (US) 1978-07-11 US claimed
WO-2020140109-A1 HIGH TEMPERATURE, CONDUCTIVE THERMOSETTING RESIN COMPOSITIONS Henkel IP & Holding GmbH (DE) 2020-07-02 WO disclosed
US-10676493-B2 Phosphorus-containing compound, phosphorus-containing flame retardant, preparation method thereof, and article made therefrom ELITE ELECTRONIC MATERAL (KUNSHAN) CO., LTD. (CN) 2020-06-09 US disclosed
US-9512333-B2 Phosphoric acid resistant polymaleimide prepolymer compositions HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2016-12-06 US disclosed
US-9296931-B2 Two-component structural adhesive which is impact resistant at room temperature SIKA TECHNOLOGY AG (CH) 2016-03-29 US disclosed
US-9212251-B2 Amino group terminated impact strength modifier and use thereof in epoxy resin compositions SIKA TECHNOLOGY AG (CH) 2015-12-15 US disclosed
EP-2417168-B1 PHOSPHORIC ACID RESISTANT POLYMALEIMIDE PREPOLYMER COMPOSITIONS HUNTSMAN ADV MAT AMERICAS INC (US) 2014-11-26 EP disclosed
US-8859695-B2 Activator for epoxy resin compositions SIKA TECHNOLOGY AG (CH) 2014-10-14 US disclosed
EP-2710045-A1 HALOGEN FREE THERMOSET RESIN SYSTEM FOR LOW DIELECTRIC LOSS AT HIGH FREQUENCY APPLICATIONS Huntsman Advanced Materials Americas LLC (US) 2014-03-26 EP disclosed
US-20140057086-A1 Halogen Free Thermoset Resin System for Low Dielectric Loss at High Frequency Applications HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2014-02-27 US disclosed
US-5138000-A High strength molding material CIBA-GEIGY CORPORATION (US) 1992-08-11 US disclosed
EP-0457732-A1 Curable compositions CIBA-GEIGY AG (CH) 1991-11-21 EP disclosed
EP-0385937-A1 Curable blends based on aromatic bismaleinimides CIBA-GEIGY AG (CH) 1990-09-05 EP disclosed
EP-0348345-A2 Solution stable polyimide resin systems CIBA-GEIGY AG (CH) 1989-12-27 EP disclosed
EP-0227598-B1 STABLE COMPOSITIONS CONTAINING IMIDES CIBA-GEIGY AG (CH) 1989-08-02 EP disclosed
US-4749767-A IMPREGNATED YARN LAMINATE CIBA-GEIGY CORPORATION (US) 1988-06-07 US disclosed
EP-0235084-A2 Hot-curable compositions containing substituted bicyclo[2,2,1]hept-5-ene-2,3 imides of dicarboxylic acids and polymalein imide CIBA-GEIGY AG (CH) 1987-09-02 EP disclosed
US-4689378-A Stable imide-containing composition from diamino phenyl indane-bis-maleimide and alkenyl phenol CIBA-GEIGY CORPORATION (US) 1987-08-25 US disclosed
US-4678849-A PREPREGS, COMPOSITES, COATINGS CIBA-GEIGY CORPORATION (US) 1987-07-07 US disclosed
EP-0227598-A1 Stable compositions containing imides CIBA-GEIGY AG (CH) 1987-07-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10676493-B2 Phosphorus-containing compound, phosphorus-containing flame retardant, preparation method thereof, and article made therefrom P2RY11, PRPF6, PRPF40A GABRA1 393/4885GABRB2 206/4885ALOX5 426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.