Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.39 |
| ▸ | HTR2C | P28335 | 4/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | HTR2B | P41595 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 3/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8052224 | 0.82 | HTR2A (0.33) | HTR2CHTR2AHTR2BL3MBTL1 | |
| SCHEMBL8045519 | 0.81 | MTNR1A (0.38) | MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL7209043 | 0.81 | L3MBTL1 (0.35) | L3MBTL1 | |
| SCHEMBL10509049 | 0.81 | L3MBTL1 (0.35) | L3MBTL1 | |
| SCHEMBL27617088 | 0.69 | L3MBTL1 (0.35) | L3MBTL1 | |
| SCHEMBL15882382 | 0.69 | L3MBTL1 (0.43) | L3MBTL1 | |
| SCHEMBL1143507 | 0.67 | HTR2C (0.45) | MTNR1AMTNR1BHTR2CHTR2AHTR2B | |
| SCHEMBL5723418 | 0.67 | L3MBTL1 (0.39) | L3MBTL1 | |
| Fluoride SCHEMBL27841384 | 0.66 | CA2 (0.47) | SIGMAR1HTR1DHTR1A | |
| SCHEMBL27781889 | 0.65 | MTNR1A (0.48) | MTNR1AMTNR1BHTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100268-A | MIGRAINES | JANSSEN PHARMACEUTICA, N.V. (BE) | 2000-08-08 | — | — | US | disclosed |
| EP-0714396-A1 | VASOCONTRICTIVE DIHYDROBENZOPYRAN DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995005383-A1 | VASOCONTRICTIVE DIHYDROBENZOPYRAN DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1995-02-23 | — | — | WO | disclosed |